This is a very, very, dangerous, dangerous, and sensitive topic, but, because so many individuals especially here in America are suffering, in the available words the English language provides, I will attempt at putting out a few words that might help a few folks out.
One of the first questions that may come to people's minds is, why are so many people suffering from Parkinson's Disease, and others like it, where the 'cause' or 'source' of the disease is still medically 'unknown', and a viable, definitive cure is 'unknown'? Or so much of this is thought.
Before getting into that, a quick recap of what Parkinson's disease is, and from there, some readers might already be able to pick up on a few threads of where this might be going, and even improve a medical situation.
These definitions are a few of many, selected from among the top of recent Google search results:
'Parkinson's disease is a progressive movement disorder of the nervous system. It causes nerve cells (neurons) in parts of the brain to weaken, become damaged, and die, leading to symptoms that include problems with movement, tremor, stiffness, and impaired balance. As symptoms progress, people with Parkinson’s disease (PD) may have difficulty walking, talking, or completing other simple tasks.' https://www.ninds.nih.gov/health-information/disorders/parkinsons-disease
'Parkinson’s disease is a brain disorder that causes unintended or uncontrollable movements, such as shaking, stiffness, and difficulty with balance and coordination.' https://www.nia.nih.gov/health/parkinsons-disease/parkinsons-disease-causes-symptoms-and-treatments
'Parkinson disease (PD) is a brain condition that causes problems with movement, mental health, sleep, pain and other health issues.' https://www.who.int/news-room/fact-sheets/detail/parkinson-disease
Those 3, should give you a rough idea, of just the definition, not the symptoms, not who it affects, just the start up of saying what it is.
Now, take note of what has been noticed, when did Parkinson's Disease make its debut?
Consider that mankind, giving it a rough estimate, over 5000 years, over 7000 years, pick a number, depending on what chronology you go by, 70,000 of today's years but by time evaluations from far back it seemed shorter, ..., all besides the point, but forms a contrast, let's just say earth and mankind have been around a very long time.
Where was Parkinson's Disease 1000 years ago, or 4000, years ago, or Mr Parkinson?
I haven't read a medieval history book that says from year 1400 to 1500, or 1100BC to 1120BC, again pick a number from a few hundred years ago or more,- there was a spate or epidemic of Parkinson's Disease in the Province of yada yada.
'Parkinson's disease was first medically described as a neurological syndrome by James Parkinson in 1817, though fragments of Parkinsonism can be found in earlier descriptions (Parkinson 1817).' https://pmc.ncbi.nlm.nih.gov/articles/PMC3234454/#:~:text=Parkinson's%20disease%20was%20first%20medically,Parkinson's%20disease%20(Parkinson%201817).
Longer excerpt does say:
EARLY CLINICAL DESCRIPTIONS
Defining Parkinson's Disease
Parkinson's disease was first medically described as a neurological syndrome by James Parkinson in 1817, though fragments of Parkinsonism can be found in earlier descriptions (Parkinson 1817). As examples, Sylvius de la Boë wrote of rest tremor, and Sauvages described festination (Sylvius de la Boë 1680; Sauvages 1768; Tyler 1992). Much earlier, traditional Indian texts from approximately 1000 BC and ancient Chinese sources also provide descriptions that suggest Parkinson's disease (Manyam 1990; Zhang et al. 2006). In succinct and pithy English, Parkinson captured the clinical picture:
Involuntary tremulous motion, with lessened muscular power, in parts not in action and even when supported; with a propensity to bend the trunk forward, and to pass from a walking to a running pace: the senses and intellects being uninjured.
https://pmc.ncbi.nlm.nih.gov/articles/PMC3234454/#:~:text=Parkinson's%20disease%20was%20first%20medically,Parkinson's%20disease%20(Parkinson%201817).
Focusing mainly on the US.
Today in 2024:
"Nearly one million people in the U.S. are living with Parkinson's disease (PD). This number is expected to rise to 1.2 million by 2030. Parkinson's is the second-most common neurodegenerative disease after Alzheimer's disease.
Nearly 90,000 people in the U.S. are diagnosed with PD each year.
More than 10 million people worldwide are living with PD."
https://www.parkinson.org/understanding-parkinsons/statistics
What happened?
And also, who mainly gets Parkinson's?:
"The incidence of Parkinson’s disease increases with age, but an estimated four percent of people with PD are diagnosed before age 50.
Men are 1.5 times more likely to have Parkinson's disease than women."
https://www.parkinson.org/understanding-parkinsons/statistics
Okay- that might've taken up a lot more time and space than necessary, but, if there are any fallbacks, validation issues, so forth, the abovesaid has 'sources cited'.
In summary, Parkinson's affects older men.
So it came to me recently, as well as over at least decade recurringly, the business about Parkinson's, and the 'unknown' cause/cure business.
My upbringing was one that hold everything has a cure. It also included that everything has a cause even if it be the Supreme Creator, your Lord, and other reference titles, was the cause. Hence, ultimately there was a cause, it is just that in cases where ascertainment of each and every step in the cause has not been made or made yet. maybe it is hidden, maybe one refuses to accept the truth about how a disease or illness became present, denied the cause, not advanced yet, veiled form seeing it, and so forth/ other descriptions.
What has been noticed are 2 standout things:
- Reiterting, Parkinson's affects older men
- It may be plausible that aspects of the history of the United States has something to do with Parkinson's rates; whereat, impacts of Isa/Jesus on the US, could be in the discussion.
As I said, it is very sensitive anytime one is talking about a Prophet; however, the rollout in a timeline might have aspects that make sense.
Today, I went to validate my very strong hunch about something: the Paroxetine, a 'medicine', is used to help 'cure' or combat the symptoms of certain kinds of erratic behaviors considered 'abnormal', a deviance from healthy, etc., whereat it is somehow going to show similar lines to Parkinson's, if not even minimally have tenous connections to it.
The result of Paroxetine is to get the patient/recipient/user into a modality of behavior and condition.
What are those 'healthy'/normal conditions?
Now reference, for example, 'the stillness' discussed in the 'Bible'.
Now also, this is today's English.
Think for a moment, today's English, in what the terms mean, in consideration of words written maybe hundreds of years back and what they meant then, and translation after translation, after version after version, of 'the Bible' [not really going into the Injeel, Gospels etc. too deep here], and then the time, say roughly 1,990 years ago [2024 minus about 30 plus years old], when most folks consider the Injeel to be making its way, -basically.
Now reflect on the history of America. Yes, there were American Indian, Natives, and Arabs for instance that were in America long ago, and so forth; but generally today, in the mainstream of what we have, is a sequence of events that has, males, especially the ones that have economic solidity, whose ancestry might have had branches that go back to waves of immigration from regions where 'Bible' ruled. For example, they came from England around 1700. Potato Famine immigration era from Ireland.
Ways of the Bible were for a long time, a large part of what influenced the ways America was run.
What made a 'dignified man', [in certain eras,] may have been at least the effort, of the way Isa/Jesus.
How many times has it been seen here in the US, a situation where a man between 60 and 75, that was family man, grandfather of dozens of kids, has a long and celebrated work history, a community leader, a reliable source and standard for thousands of people to seek guidance from, suddenly undergo dropping to the ground, or did not emerge from rest, only to forever further, be in a slouched manner or overly taut condition, and then comes a cycle of ongoing medication? He is the hero no more?
Yes, there are parables that man begins a clot, then becomes reduced at old age; there is a borderline bubble between still too young to go all the way down to suddenly a condition of medical liability with no ability to help others, especially when it could have been moderately easy to prevent, and the natural shrinkage of old age.
More knowledge [seeking]
Stillness, austerity, manliness, these are all qualities that men of generations born in the 1950s and earlier find admirable.
However, there may be times where there is an understanding of these, that can help preempt unnecessary suffering.
For example, a tense muscle tone.
Some males may find it necessary to hold their biceps in tense state 24 hours a day, as they believe that will help the muscles 'look bigger', stay stronger, and thus, look more manly. They never relax it. Maybe some when they go to sleep.
Then there is the frame of mind, the medical cathexis, or 'rigid holding onto' certain ideals, or sub-ideals.
What might wind up happening, is total rigidity, is a state upheld in the mind, that must be, in order to uphold the quality, or spiritual quality, of a dimension of being a rigid and masculine man, while not woman-like. (Reference Leviticus and other areas of 'today's Bible in English'.)
Taking a look at health standards, the tonal states of man change, muscles relax when they go to sleep, muscles build, breakdown, build back up, etc., so they can grow and be larger, without having to flex all day in order to succeed in showing off.
But if a person is so attached to having all muscles rigid all day, it might actually prevent the higher level of health.
It is along those lines of sequences of events, that illnesses with symptoms like Parkinson's could start to creep on in.
Other areas in the list include, phrases like 'suppress the baser self', fight the snakes within you', ignoring pain and driving forward, behaviors that lead to sleep deprivation, well-intended, like working everyday triple overtime 'to feed a family', and so on.
Suggested studies
A specific area of study might be similarities of Paroxetine side effects to symptoms of Parkinson's, as well as exacerbations.
Citing:
"Paroxetine, a selective serotonin reuptake inhibitor, is a widely used antidepressant drug. It can effectively inhibit presynaptic 5-HT uptake and increase 5-HT level in the synaptic cleft of neurons, consequently alleviating depressive disorder and anxiety in PD patients. At the same time, the neurotransmitter activity of 5-HT is enhanced, which can effectively ameliorate motor function. Therefore, paroxetine can not only relieve the symptoms of depression and anxiety, but also contribute to the recovery of neurological function."
From The effects of paroxetine therapy on depressive symptom and motor function in the treatment of depression with Parkinson’s disease: A meta-analysis
2023 Aug 25;102(34):e34687. doi: 10.1097/MD.0000000000034687
Li-Lin Jiang, Yu-Lin Wu, Ye Mo, Ling Gou, Mei-Ling Chen, Yan Wang, Qing-Min Zang, De-Qi Jiang
https://pmc.ncbi.nlm.nih.gov/articles/PMC10470685/#:~:text=It%20has%20been%20found%20that,action%20and%20no%20obvious%20cardiotoxicity.&text=Nowadays%2C%20paroxetine%20is%20used%20for,in%20the%20treatment%20of%20dPD.
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Article abstract: 'Selective serotonin reuptake inhibitors have been used in the treatment of depression in patients with PD. Conflicting data as to whether selective serotonin reuptake inhibitors worsen parkinsonian motor symptomatology have been reported. In this study, the additional 6 months therapy with paroxetine 20 mg/d in a group of depressed patients with PD did not modify parkinsonian motor function (Unified Parkinson’s Disease Rating Scale scores); however, in one patient, fully reversible worsening of tremor was observed.'
Paroxetine in Parkinson’s disease: Effects on motor and depressive symptoms
R. Ceravolo, MD, A. Nuti, MD, A. Piccinni, MD, G. Dell’ Agnello, MD, G. Bellini, MD, G. Gambaccini, MD, L. Dell’ Osso, MD, L. Murri, MD, and U. Bonuccelli, MD
October 24, 2000 issue
Conflicts of interest, or not conflictng, or much more science as more studies are performed will shape up the arena, the ballpark points to a consistent theme of rigidity/tonality, especially physiological.
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Brain imaging and brain spaces
'Recent studies associate findings of dVRS with parkinsonism'2
'Virchow–Robin spaces are perivascular, interstitial fluid-filled spaces surrounding cerebral vessels passing from the subarachnoid space through the brain parenchyma'
[translated? from Spanish to English]
Relación de los espacios de Virchow-Robin con la enfermedad de Alzheimer: a propósito de un caso ... Espacios de Virchow–Robin. ¿una causa de parkinsonismo? (2016)
MRI etc.
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Vagaries of behaviors just before and after sleep of Parkinson's patients
When someone, pertinently an adult with life decision making capacity, such as where to buy a house, is first exposed to a parent going through an episode, a 'religious' person's reaction might be to say certain prayers; when that doesn't work, a series of events may occur involving consulting different doctors, hospital admittances, drug and medicine selection, some which might fail and lead to other problems.
This is a lead in to a big lever, affecting potential outcomes of better or worse: how real, how good, how knowledgeable are the doctors that gave advice? Are they leaving you hooked onto to them to drain promised money but barely know what they are talking about? You cannot get led down a faulty path when your parents' health is at stake. Ask the right questions to be able to accurately gage the abilities of the doctor for the area that you need.
[Taking steps]
An entire book could be written on this subject, going on and on about the meanings of Paroxetine, and other medicines. For now, the suggestion is the standard, seek understanding of the Injeel and other Books, such as Quran and Torah, perhaps Zabur and so on, depending on where you are going, and seek knowledge and understanding of health states and conditions.
Speaking of where you are going, where one should be headed, sometimes the initial goal is not the same goal later in life after more learning. For instance, young guy might say, I want a fast car, fancy house, hot female accomplice, medium aged guy a little older says, I want a dependable car, a faithful wife, a solid income, and real estate at no risk of getting away, older guy says he wants to leave a family legacy.
At some point, some men striving on paths, such as to be like some of what they heard or read about, about Isa/Jesus, might learn from sources available, and it may become a goal, but is the layer of meaning of that goal, really the condition that should stay the goal, especially if a higher level of understanding alters the shape?